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All research and
development (R & D) at AT-GC is focused on the goal of developing integrated &
comprehensive treatments that will make a quantitative difference in patients’
lives. We believe that the best way to accomplish this
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is to develop a
clear understanding of disease epidemiology– the networks of molecular
mechanisms that underlie diseases. By combining this understanding with
knowledge of therapeutically important differences that may exist between
patients – differences either in disease pathways or in their responsiveness to
particular drugs – we seek to enable “personalized medicine." By this we mean
providing the right drugs, directed toward the right molecular targets, to the
right patients, at the right time. Our approach is significantly different from
other personalized medicine platforms that utilize patients genetic information
to tailor novel drugs. Our proprietary
doctor DNA TM
platform technologies, utilizes patients own metabolic environment to synthesize
the personalized drug. We feel very strongly that such an approach will take in
to account all the variables that exist in the patient’s body to tailor the drug
for maximum onsite efficiency.
Pipeline
The
value of our focus on diseases with enormous global disease burden is
illustrated by the pipeline of potential drugs we have in pre-clinical
development, which includes molecules targeted to several key areas: Cancer
therapeutics, infectious disease treatment, multi drug resistant infections and
bio-defense.
R&D
Platform
To
add to our clinical pipeline, we have a large number of discovery-stage and
preclinical programs, all driven by a powerful R&D engine that combines
world-class biology in important disease pathways with an industry-leading
technology platform. Over the last decade, this combination has made Avanti
Therapeutics the partner of choice for many major pharmaceutical companies
seeking to enhance their R&D productivity.
Therapeutic
Areas of focus
R&D
programs at AT-GC are focused in four key therapeutic areas, encompassing a
range of important diseases:
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